Gut Microbiota in Stunted Children

Hervina Hervina, Kadek Lusi Ernawati, Ni Kadek Ari Astuti

Abstract


Stunting is a condition of failure to thrive in children under five which is characterized by a lack of height compared to other children of their age. Although there was a decrease in the proportion of stunting from 37.2% in 2013 to 30.8% in 2018, this figure is still far from the target of  WHO, which is 20%. In stunted children, there is a change in the intestinal microbiota which causes disruption of nutrient absorption, leading to malnutrition. The microbiota in healthy children contains many probiotic species such as Bifidobacterium longum and Lactobacillus mucosae, while in stunted children there are many inflammogenic taxa such as the genus Desulfovibrio. the order of Campylobacterales, E. coli, Firmicutes, Proteobacteria, and Bacterioides.

Keywords


Gut; Microbiota; Stunting

References


Arrieta, M. et al. (2014) ‘The intestinal microbiome in early life : health and disease’, 5(September), pp. 1–19. doi: 10.3389/fimmu.2014.00427.

Dinh, D. M. et al. (2016) ‘Longitudinal Analysis of the Intestinal Microbiota in Persistently Stunted Young Children in South India’, pp. 1–17. doi: 10.1371/journal.pone.0155405.

Ghosh, T. S. et al. (2014) ‘Gut Microbiomes of Indian Children of Varying Nutritional Status’, 9(4), pp. 1–13. doi: 10.1371/journal.pone.0095547.

Helmyati, S. et al. (2017) ‘Keadaan mikrobiota saluran cerna pada anak sekolah dasar yang mengalami stunting di lombok barat (’, 12(1), pp. 55–60. doi: 10.25182/jgp.2017.12.1.55-60.

Kane, A. V et al. (2014) ‘cc ep te m an us c cc ep te d m us’. doi: 10.1038/pr.2014.179.

Kemenkes (2017) 100 Kabupaten/Kota Prioritas Untuk Intervensi Anak Kerdil (Stunting). Cetakan pe. Jakarta.

Kesehatan Kementrian (2018) Hasil Utama Riskesdas 2018. Indonesia. Available at: https://www.kemkes.go.id/resources/download/info-terkini/materi_rakorpop_2018/Hasil Riskesdas 2018.pdf.

Kumar, M. et al. (2019) ‘Gut Microbiota Dysbiosis is Associated with Malnutrition and Reduced Plasma Amino Acid Levels: Lessons from Genome- Scale Metabolic Modeling’, Metab Eng, 9(49), pp. 128–142. doi: 10.1016/j.ymben.2018.07.018.Gut.

Masrul, M. et al. (2020) ‘Microbiota Profile with Stunting Children in West Sumatera Province , Indonesia’, 8, pp. 334–340.

Ni`mah Khoirun and Nadhiroh, S. R. (2015) ‘Faktor Yang Berhubungan Dengan Kejadian Stunting Pada Balita’, Media Gizi Indonesia, 10(1), pp. 13–19. Available at: http://e-journal.unair.ac.id/index.php/MGI/article/view/3117/2264.

Nirmalasari, N. O. (2020) ‘STUNTING PADA ANAK : PENYEBAB DAN FAKTOR RISIKO STUNTING DI INDONESIA’, 14(1), pp. 19–28. doi: 10.20414/Qawwam.v14i1.2372.

Owino, V. et al. (2016) ‘Environmental Enteric Dysfunction and Growth Failure / Stunting in Global Child Health’, 138(6). doi: 10.1542/peds.2016-0641.

Robertson, R. C. et al. (2019) ‘The Human Microbiome and Child Growth – First 1000 Days and Beyond’, Trends in Microbiology. Elsevier Ltd, 27(2), pp. 131–147. doi: 10.1016/j.tim.2018.09.008.

WHO (2017) ‘Global Nutrition Targets 2025 Stunting Policy Brief’. Geneva Switzerland.




DOI: https://doi.org/10.33476/jky.v29i3.1812

Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Jurnal Kedokteran YARSI

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

__________________________________________________________________________________________

Copyright of Jurnal Kedokteran YARSI.

Powered by OJS.

Creative Commons License

This work is licensed under a Creative Commons Attribution- NonCommercial 4.0 International License.